Deqiang Duanmu
Title: Professor
Degree: Ph.D.
E-mail: duanmu@mail.hzau.edu.cn
Research Interests: Photosynthesis in Microalgae, Biological Nitrogen Fixation
Education
1995.09-1999.07, Peking University, B.S.
1999.09-2002.07, Institute of Zoology, Chinese Academy of Sciences, M.S.
2002.09-2009.07, Iowa State University, Ph.D.
Postdoctoral and Present Positions
2009.08-2014.06, Postdoc, University of California, Davis
2014.07-present, Professor, College of Life Science and Technology, Huazhong Agricultural University
Achievements in Scientific Research
Research Interests
The main research areas include: (1) Molecular mechanisms of photosynthesis of microalgae and chloroplast signal transduction; (2) Molecular networks of legume-rhizobia symbiosis and efficient nitrogen fixation in nodules; (3) Genome editing and chloroplast biotechnology; (4) Reconstructing microbial photosynthetic system by synthetic biology approaches.
Academic Achievements
I have published more than 20 research and review papers and many articles have been published in top journals such as PNAS, Plant Cell, and New Phytologist. The research in the lab has focused on the biological functions of chloroplast signal molecules: 1）clarifying the mechanism of bilin in Chlamydomonas as chloroplast retrograde signal to regulate the expression of genes related to reactive oxygen metabolism; 2) revealing that bilin has effects on chlorophyll biosynthesis and photosystem I protein accumulation; 3) analyzing the degradation pathway of heme in nodules and the mechanism by which leghemoglobins promote efficient nitrogen fixation in nodules.
Support and grants
1. National Natural Science Foundation of China, Molecular Mechanisms of Heme Oxygenase LjHO1 in Maintaining Efficient Nitrogen Fixation in Nodules (31870220), 2019/01-2022/12, ￥600,000.
2. National Natural Science Foundation of China, Molecular mechanism of bilin-mediated chloroplast retrograde signal transduction (31570233), 2016/01-2019/12,￥756,000.
3. Huazhong Agricultural University, Molecular mechanisms of leghemoglobins in regulating nodule development and nitrogen fixation (2662015PY171), 2015/09-2020/09, ￥200,000.
Selected Publications
1. Huang R, Li Z, Mao C, Zhang H, Sun Z, Li H, Huang C, Feng Y, Shen X, Zhang Z, Lin Y, Cao Y#, Duanmu D#. Natural variations at OsCERK1 regulate arbuscular mycorrhizal symbiosis in rice. New Phytol, 2020, 225(4):1762-1776.（Co-corresponding Author）
2. Wang L, Maria C, Xin X, Zhang B, Fan Q, Wang Q, Ning G, Becana M, Duanmu D. CRISPR/Cas9 knockout of leghemoglobin genes in Lotus japonicus uncovers their synergistic roles in symbiotic nitrogen fixation. New Phytol, 2019, 224(2):818-832.（Corresponding Author）
3. Ji J, Zhang C, Sun Z, Wang L, Duanmu D#, Fan Q#. Genome Editing in Cowpea Vigna unguiculata Using CRISPR-Cas9. Int J Mol Sci, 2019 May 19; 20(10). pii: E2471.（Co-corresponding Author）
4. Cai K, Yin J, Chao H, Ren Y, Jin L, Cao Y, Duanmu D# and Zhang Z#. A C3HC4-type RING finger protein regulates rhizobial infection and nodule organogenesis in Lotus japonicus. J Integr Plant Biol, 2018, 60(9):878-896.（Co-corresponding Author）
5. Zhang W, Zhong H, Lu H, Zhang Y, Deng X, Huang K, Duanmu D#. Characterization of Ferredoxin-dependent Biliverdin Reductase PCYA1 Reveals the Dual Function in Retrograde Bilin Biosynthesis and Interaction with Light-dependent Protochlorophyllide Oxidoreductase LPOR in Chlamydomonas reinhardtii. Front Plant Sci, 2018, 9:676.（Corresponding Author）
6. Wittkopp TM, Schmollinger S, Saroussi S, Hu W, Zhang W, Fan Q, Gallaher SD, Leonard MT, Soubeyrand E, Basset GJ, Merchant SS, Grossman AR, Duanmu D#, Lagarias JC#. Bilin-dependent photoacclimation in Chlamydomonas reinhardtii. Plant Cell, 2017, 29(11):2711-2726.（Co-corresponding Author）
7. Wang L, Wang L, Zhou Y, Duanmu D#. Use of CRISPR/Cas9 for Symbiotic Nitrogen Fixation Research in Legumes. Prog Mol Biol Transl Sci, 2017, 149:187-213.（Corresponding Author）
8. Duanmu D#, Rockwell NC, Lagarias JC#. Algal Photomorphogenesis and Light Sensing in Aquatic Environments. Plant Cell Environ, 2017, 40(11):2558-2570.（First author＆Co-corresponding Author）
9. Wang L, Wang L, Tan Q, Fan Q, Zhu H, Hong Z, Zhang Z#, Duanmu D#. Efficient Inactivation of Symbiotic Nitrogen Fixation Related Genes in Lotus japonicus Using CRISPR-Cas9. Front. Plant Sci, 2016, 7:1333（Co-corresponding Author）
10. Duanmu D*, Bachy C*, Sudek S, Wong CH, Jimenez V, Rockwell NC, Martin SS, Ngan CY, Reistetter EN, van Baren MJ, Price DC, Wei CL, Reyes-Prieto A, Lagarias JC, Worden AZ. Marine algae and land plants share conserved phytochrome signaling systems. Proc Natl Acad Sci USA, 2014, 111(44):15827-15832.（Co-first author）
11. Duanmu D, Casero D, Dent RM, Gallaher S, Yang W, Rockwell NC, Martin SS, Pellegrini M, Niyogi KK, Merchant SS, Grossman AR, Lagarias JC. Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival. Proc Natl Acad Sci USA, 2013, 110(9):3621-3626.（First author）
12. Duanmu D, Spalding MH. Insertional suppressors of Chlamydomonas reinhardtii that restore growth of air-dier lcib mutants in low CO2. Photosynth Res, 2011,109 (1-3):123-132.（First author）
13. Duanmu D, Miller AR, Horken KM, Weeks DP, Spalding MH. Knockdown of limiting-CO2-induced gene HLA3 decreases HCO3- transport and photosynthetic Ci-affinity in Chlamydomonas reinhardtii. Proc Natl Acad Sci USA, 2009, 106(14):5990-5995.（First author）
14. Duanmu D, Wang Y, Spalding MH. Thylakoid lumen carbonic anhydrase (CAH3) mutation suppresses air-Dier phenotype of LCIB mutant in Chlamydomonas reinhardtii. Plant Physiol, 2009, 149(2):929-937.（First author）
Note
I am currently serving as a council member of the Chinese Society of Plant Biologists (Photosynthesis Research Committee), Hubei Provincial Microbiology Society, and Hubei Provincial Genetics Society.
