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赵开弘
发布人:发布时间:2020-03-16


职称 教授

学位 博士

政治面貌 中共党员

电话 027-87284301

邮箱 khzhao@163.com

研究方向 蓝细菌光合作用与蛋白质工程


教育经历

1980.09-1984.07,武汉大学,理学学士

1984.09-1989.07,中国科学院感光化学研究所,理学博士


主要职历

1989.08-1994.09,中国科学院感光化学研究所,助理研究员

1991.04-1993.08,德国洪堡基金 慕尼黑大学,博士后

1993.09-1994.09,瑞士弗莱堡大学,博士后

1994.10-2000.06,武汉大学,教授

2000.07-2008.07,华中科技大学,教授

2008.08-现在,华中农业大学,教授(二级岗)


科研成果

代表性学术论文

1. Li XD, Tan ZZ, Ding WL, Hou YN, Kong CD, Zhao BQ, Zhao KH*. Design of small monomeric and highly bright near-infrared fluorescent proteins. Biochim Biophys Acta Mol Cell Res 2019, 1866(10):1608-1617

2. He Q, Tang QY, Sun YF, Zhou M, Gartner W, Zhao KH*. Chromophorylation of cyanobacteriochrome Slr1393 from Synechocystis sp. PCC 6803 is regulated by protein Slr2111 through allosteric interaction. J Biol Chem 2018, 293(46):17705-17715

3. Zhao C, Hoppner A, Xu QZ, Gartner W, Scheer H, Zhou M, Zhao KH*. Structures and enzymatic mechanisms of phycobiliprotein lyases CpcE/F and PecE/F. Proc Natl Acad Sci USA 2017, 114(50):13170-13175

4. Miao D, Ding WL, Zhao BQ, Lu L, Xu QZ, Scheer H, Zhao KH*. Adapting photosynthesis to the near-infrared: non-covalent binding of phycocyanobilin provides an extreme spectral red-shift to phycobilisome core-membrane linker from Synechococcus sp. PCC7335. Biochim Biophys Acta - Bioenerg 2016, 1857(6):688-694

5. Tang K, Ding WL, Hoppner A, Zhao C, Zhang L, Hontani Y, Kennis JT, Gartner W, Scheer H, Zhou M, Zhao KH*. The terminal phycobilisome emitter, LCM: A light-harvesting pigment with a phytochrome chromophore. Proc Natl Acad Sci USA 2015, 112(52):15880-15885

6. Zeng XL, Ren Z, Wu Q, Fan J, Peng PP, Tang K, Zhang RQ, Zhao KH*, Yang X*. Dynamic crystallography reveals early signalling events in ultraviolet photoreceptor UVR8. Nature Plants 2015, 1:14006

7. Zeng XL, Tang K, Zhou N, Zhou M, Hou HJ, Scheer H, Zhao KH*, Noy D*. Bimodal intramolecular excitation energy transfer in a multichromophore photosynthetic model system: hybrid fusion proteins comprising natural phycobilin- and artificial chlorophyll-binding domains. J Am Chem Soc 2013, 135(36):13479-13487

8. Chen Y, Zhang J, Luo J, Tu JM, Zeng XL, Xie J, Zhou M, Zhao JQ, Scheer H, Zhao KH*. Photophysical diversity of two novel cyanobacteriochromes with phycocyanobilin chromophores: photochemistry and dark reversion kinetics. FEBS J 2012, 279(1):40-54

9. Zhao KH, Porra RJ, Scheer H. Phycobiliproteins. In: Roy S, Skarstad Egeland E, Johnsen G, Llewellyn CA, editors. Phytoplankton Pigments: Characterization, Chemotaxonomy and Applications in Oceanography. Cambridge: Cambridge University Press; 2011. p. 375-411

10. Zhang J, Wu XJ, Wang ZB, Chen Y, Wang X, Zhou M, Scheer H, Zhao KH*. Fused-gene approach to photoswitchable and fluorescent biliproteins. Angew Chem Int Ed Engl 2010, 49(32):5456-5458


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